Introduction

OneFul's mission is to make personalized medicine and clinical nutrition more effective based on science, affordable, and accessible to all.

The company was founded by an experienced multiple-exit entrepreneur who is an inventor of robotics and factory automation. The professional team is led by pharmacists, regulatory experts, and big pharma drug developers who believe that e-pharmacy and modernized manufacturing technology can make Little Pharmacy the leader in democratizing medicine.

Problem

U.S. adults take four medications a day on average, elderly take over five, causing confusion and leading to essential medications not being taken, often leading to tragic events. Big Pharma’s one-size-fits-all approach can lead to dangerous side effects and ineffective medications.

Solution

Our patented technology platform scales the production of individualized treatments, leveraging genomic science, biomarker tests, and digital patient profiles to deliver precision treatments that are more effective and promote adherence.

We've developed safe and effective cardiovascular polypill formulations that improve adherence, combining 3 to 7 approved drugs into standard capsule forms. Fixed combination polypills have been shown in over 30,000 patients to reduce the risk of cardiovascular events by an average of 50% annually. Fixed polypills have been poorly accepted internationally and are unavailable in the USA. OneFul's CVD-P3 precision individualized polypill is one of the first personalized cardiovascular preventatives.

Modern genomic science and biomarker tests can now inform how personalized medicines work better. OneFul can use a pharmacogenomic generated from a cheek swab home test along with other biomarkers like a home blood test to create a digital profile for each individual. This allows our PharmDs to suggest the right drugs at the right doses so that your medications are more effective and with fewer adverse side effects.

Success To Date

  • Revenue generating at $4.0M (TTM).
  • Over 3,500 regular customers, qualified supplier of several major hospital systems, including Research Triangle NC regional hospitals.
  • Delivered one of the first personalized cardiovascular polypills, ready to scale nationally.
  • Partnerships with telemedicine prescribers and home test suppliers.
  • 13 issued patents with more in process.
  • Accredited 503A compounding facility, currently licensed in nine states.
  • Global potential with international licenses in place, more in discussion.
  • Expert management team with specialist technical, regulatory, and financial skill set.
  • CEO founder has multiple exits.

Business Model

OneFul operates as an e-pharmacy, filling custom prescriptions for individuals created online by telemedicine physicians and healthcare systems, including hospitals. We leverage emerging market channels like telemedicine, partnering with industry leaders to provide potential patients easy access to medical advice and testing services. We believe this strategy bypasses the traditional detailing sales costs of bringing new therapeutic products to market the existing patient populations of the telemedicine providers. 

Our 503A pharmacy services over 3,500 individuals annually, many of whom are candidates for our CVD-P3 polypill. Over 300 people have completed the polypill qualification online survey, with a growing set of patients on our waitlist.

The global personalized medicine market size is projected to reach over US $5.7 trillion by 2030, expanding growth at a noteworthy CAGR of 11.6%.
---

Market

For consumers managing chronic diseases and conditions, current drug therapies typically consist of multiple medications, requiring patients to take as many as 3-7 pills per day. According to recent data, 24% of adults in the U.S. take more than 3 pills per day, and the rate of adherence to prescribed treatments is less than 50% (source, source), resulting in at least 100,000 preventable deaths and $100B in preventable medical costs per year (source). The market size for personalized or precision medicine in the USA may grow significantly in the coming years.

Team

Edison T Hudson
CEO/CTO/Board Member/Founder
Edison is a serial entrepreneur with multiple exits and IPO experience. He is also recognized as a prolific inventor with over 30 patents, spending over 15 years in semiconductor automation in Silicon Valley and the EU. At iRobot Corporation, as Director of Research, he participated on the IPO team and led new business acquisitions and strategic technology roadmap analysis. His engineering and computer science expertise combines street-savvy business acumen, having concluded dozens of technology licenses and partnership agreements. He is a lifelong learner and researcher, a Morehead Scholar at the University of North Carolina, an MBA from Duke University, and studied machine learning and robotics at Oxford University U.K., where he spun out his first company. An excellent communicator, he was a speaker at the 2022 Precision Medicine World Conference in Silicon Valley. His passion and vision are that robotics and machine learning can democratize health using low-cost, safe, and more effective personalized treatments. He has assembled a team of experts and operational management that can leverage post-pandemic regulatory change. This team and his inventions are the foundation for a scalable digital health paradigm, economically delivering the benefits of personalized medicine to millions.
Danny M Barnes
Chief Pharmacy Officer, Board Member, President Triangle Compounding Pharmacy
Danny has spent the last 20 + years focused on serving patients and physicians with personalized sterile and non-sterile medications for complex needs. As president and operational executive of Triangle Compounding Pharmacy (TCP), the wholly owned compounding pharmacy operation of Oneful, he drove TCP to be the first compounding pharmacy in NC to meet national standards and be accredited by the Pharmacy Compounding Accreditation Board (PCAB). TCP was the first compounding pharmacy in NC to be registered as a Human Drug Outsourcing Facility (503B) to help physicians and hospitals meet critical patient needs by compounding crucial medications during drug shortages. Danny received his Pharm.D. from Campbell University and his Zoology degree at NC State University. As Chief Pharmacy Officer of Oneful Health, he is passionate about implementing cGMP quality robotic automation to modernize compounding pharmacy. His devotion to the highest quality products and services has generated a large, loyal community of patients and healthcare systems. He shares his regulatory and operational expertise through activities with state and national pharmacy organizations. (Fulltime Employee) 

Use of Proceeds


If the offering's maximum amount of $536,500 is raised:

UseValue% of Proceeds
Company Employment$134,12625.0%
Marketing / Promotions$134,12525.0%
Inventory$53,65010.0%
Product Development$80,47515.0%
General and Administrative$53,65010.0%
CAPEX - Facility$54,18710.1%
Intermediary fees$26,2894.9%

Terms

This is an offering of Common Stock, under registration exemption 4(a)(6), in OneFul Health Inc.. This offering must raise at least $10,000 by April 26, 2024 at 10:59pm ET. If this offering doesn’t reach its target, then your money will be refunded. OneFul may issue additional securities to raise up to $536,500, the offering’s maximum.

If the offering is successful at raising the maximum amount, then the company’s implied valuation after the offering (sometimes called its post-money valuation) will be:

10,361,948 shares
×
$1 per share
$10,361,948implied valuation

Financials

These financial statements have been reviewed by an independent Certified Public Accountant.

SEC Filings

The Offering Statement is a formal description of the company and this transaction. It’s filed with the SEC to comply with the requirements of exemption 4(a)(6) of the Securities Act of 1933.

We’re also required to share links to each of the SEC filings related to this offering with investors.

Understand the Risks

Be sure to understand the risks of this type of investment. No regulatory body (not the SEC, not any state regulator) has passed upon the merits of or given its approval to the securities, the terms of the offering, or the accuracy or completeness of any offering materials or information posted herein. That’s typical for Regulation CF offerings like this one.

Neither Netcapital nor any of its directors, officers, employees, representatives, affiliates, or agents shall have any liability whatsoever arising from any error or incompleteness of fact or opinion in, or lack of care in the preparation or publication of, the materials and communication herein or the terms or valuation of any securities offering.

The information contained herein includes forward-looking statements. These statements relate to future events or to future financial performance, and involve known and unknown risks, uncertainties, and other factors, that may cause actual results to be materially different from any future results, levels of activity, performance, or achievements expressed or implied by these forward-looking statements. You should not place undue reliance on forward-looking statements since they involve known and unknown risks, uncertainties, and other factors, which are, in some cases, beyond the company’s control and which could, and likely will, materially affect actual results, levels of activity, performance, or achievements. Any forward-looking statement reflects the current views with respect to future events and is subject to these and other risks, uncertainties, and assumptions relating to operations, results of operations, growth strategy, and liquidity. No obligation exists to publicly update or revise these forward-looking statements for any reason, or to update the reasons actual results could differ materially from those anticipated in these forward-looking statements, even if new information becomes available in the future.

More Info

Updates

  • Apr 27, 2024
    Primary offering finalized, selling 23,612 shares
    Sold 23,612 shares at $1 for a total of $23,612
  • Apr 26, 2024
    BIG PHARMA has the BIG BUCKS. Little Pharma...

    BIG PHARMA has the BIG BUCKS. Little Pharma needs much more. Only Hours to go in this campaign.

    We hoped that Crowdfunding might be a way to raise capital to help build the infrastructure that LITTLE PHARMA needs to serve up effective, safe, high-quality treatments using the enormous pharmacopeia that exist as generics. The visibility that Crowdfunding through NetCapital and StartEngine has given OneFul Health Inc has helped us get the message out that personalized, affordable medicine is coming with the aid of the type of technology that made the laser printer and the personal computer ubiquitous. We will continue to spread our message, and we are encouraged by the connections we have made with many types of investors, who are now keeping an eye on our progress, and we know will someday be our partners.

    We thank the nearly 200 small investors who have invested in our vision.

    Democratize Chronic Disease Treatments by Investing in Robotic Automation of Compounding Pharmacy!

    Can LITTLE PHARMA Compete with BIG PHARMA.pdf
  • Apr 22, 2024
    Preventative Cardiovascular PolyPills Now –...

    Preventative Cardiovascular PolyPills Now – For Alzheimer’s and Dementia – Someday Soon? Why Is It So Hard to Treat Alzheimer’s? “The brain disease has long stymied researchers. But that has begun to change, and for the first time, ways to prevent, slow and even treat the disease are emerging “(https://www.aarp.org/health/conditions-treatments/info-2024/why-is-there-no-cure-for-alzheimers.html)

    Cardiovascular diseases, including conditions like hypertension and diabetes, are linked to an increased risk of dementia, as poor cardiovascular health can lead to brain changes that contribute to cognitive decline.

    OneFul Health is working with researchers who believe that a combination polypill may provide an affordable approach based on early detection home kit.

    See article attached.

    www.netcapital.com/companies/onefulPolyPill for Alzheimers.pdf
  • Apr 12, 2024
    Better than GLP-1 Drugs: Are Endogenous GLP-1...

    Better than GLP-1 Drugs: Are Endogenous GLP-1 Medical Foods Possible? OneFul possesses technologies that enable the delivery of high doses of active ingredients to specific regions of the digestive system. Using a patent pending method of micro-encapsulation, OneFul can capture active ingredients, including short-chain fatty acids (‘SCFA’s’), and some amino acids that have been shown in multiple research publications to stimulate GLP-1 and other satiety hormones, naturally. OneFul is exploring the development of complementary treatments to the GLP-1 agonists drugs, based on recent GLP-1 incretin science. It has the proven manufacturing systems that can personalize formulations to best match and individual’s metabolism, with products adapt to the young and old medical needs.

    www.oneful.healthBetter than GLP-1 Drugs - New Concept - Endogenous GLP-1 Medical Foods.pdf
  • Apr 4, 2024
    Revolutionizing Healthcare with Cutting-Edge...

    Revolutionizing Healthcare with Cutting-Edge Technology: Despite remarkable strides in computation, genomics, robotics, and Artificial Intelligence, the battle against global health challenges remains incomplete. Noncommunicable diseases claim 41 million lives annually, accounting for a staggering 74% of all deaths worldwide. Heart attacks, strokes, diabetes, and obesity—these silent killers drain healthcare resources and hinder human potential. And yet, the science is clear that there are low cost, effective means of prevention.

    OneFul Health - Update 4-04-23.pdf
  • Mar 5, 2024
  • Jan 4, 2024
    See recent article by Edison Hudson on OneFul's...

    See recent article by Edison Hudson on OneFul’s thoughts and plans in metabolic and weight loss markets. https://www.linkedin.com/feed/update/urn:li:activity:7147705277612519424/

    www.oneful.health
  • Dec 28, 2023
    OneFul has begun to expand its cardio-metabolic...

    OneFul has begun to expand its cardio-metabolic products beyond the CVD polypill to include diabetes and obesity prevention, addressing the exploding market for such medications (link). Our accredited pharmaceutical facility, TriangleCompounding.com, is now filling prescriptions for FDA-approved form of semaglutide, the active ingredient of popular drugs Ozempic and Wegovy. In November, we completed the buy-back of Panaceutics.com, a supplier of personalized nutrition and clinical foods. This will enable us to offer personalized medical foods and clinical products through licensed prescriber channels. For example, Panaceutics has supplied squeeze pouch products serving gut health with specialized ingredients that create small-chain fatty acids, known to naturally stimulate GLP-1, the same hormone mimicked by the injected drugs. OneFul has begun the development of GLP-OneFul™, a personalized GLP-1 agonist oral product. We plan to use some of the NC funding to support a 2024 pilot.

    https://markets.businessinsider.com/news/stocks/ozempic-anti-obesity-market-weight-loss-novo-nordisk-goldman-sachs-2023-11
  • Dec 20, 2023
    Primary offering of 536,500 shares at $1
  • Dec 20, 2023

Ask a Question

Proofread your comment before submitting: once it's posted, you can’t edit or delete it. Investors are advised to review our Discussion Board Policy before submitting a comment. For the fastest help with the web site, email help@netcapital.com instead of commenting.

Looking to raise capital?
We can help turn your friends, family and customers into investors.

Learn more

Interested in more investment opportunities?
Browse all offerings currently available.

See more